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Updated: Feb 10, 2026

A Preterm Rat Model for Pain Studies
Published on: February 9, 2024
Post-tonsillectomy pain and bupivacaine, an intra individual design study
Amer Sabih Hydri1, Sher Muhammad Malik
1Department of ENT, Combined Military Hospital, Pano Aqil. draamerhydri@gmail.com
Objective:
To compare whether an individual could appreciate the pain relief, if any, in either one of his/her tonsillar fossa topically suffused with a local anaesthetic (bupivacaine).
Study Design:
Randomized controlled trial.
Place And Duration Of Study:
Department of ENT/Head and Neck Surgery, Combined Military Hospital, Peshawar, from January to June 2007.
Methodology:
Forty-six patients of either gender, aged 10-42 years undergoing tonsillectomy for recurrent tonsillitis were enrolled for this study. At the end of surgery, having secured haemostasis, one tonsillar fossa was randomly packed with a gauze piece soaked in 3 ml of 0.5% bupivacaine for 5 minutes, while the other was not. Effects of postoperative analgesia were assessed using visual analogue scale (VAS) up to 8 hours.
Results:
Majority of the patients (85%, n=39) failed to experience an appreciable pain relief on the side of local anaesthetic (bupivacaine) application (p=0.006).
Conclusion:
Topical application of local anaesthetic (bupivacaine) confers no appreciable pain control in post-tonsillectomy patients.
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