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Published on: March 5, 2010
Cutaneous CD30 positive anaplastic large cell lymphoma
1Department of Dermatology, Pilgrim Hospital, Lincolnshire, UK. mdilnawaz@gmail.com
Summary
A solitary thigh lesion initially mimicking an infection was diagnosed as CD30-positive anaplastic large cell lymphoma. This localized cutaneous lymphoma was treated effectively with radiotherapy.
Area of Science:
- Dermatology
- Oncology
- Pathology
Background:
- Cutaneous lymphomas can present as solitary lesions, posing diagnostic challenges.
- Differential diagnoses for skin lesions include infections and inflammatory processes.
Observation:
- An adult male presented with a solitary, ulcerated thigh lesion with a central eschar.
- Initial considerations included deep mycosis, insect bite reaction, and atypical mycobacterial infection.
Findings:
- Histological examination confirmed a CD30-positive anaplastic large cell lymphoma.
- Hematology-oncology screening was performed.
Implications:
- Localized cutaneous lymphomas can be managed with radiotherapy or surgical excision.
- Systemic treatment is indicated for generalized disease.
- Prognosis is contingent upon the extent of lymphomatous involvement.
