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Updated: Jun 10, 2026
Application of Mid-Pancreatectomy with End-to-End Anastomosis in Pancreatic Benign Tumors
Published on: February 9, 2024
Indications and early outcomes for total pancreatectomy at a high-volume pancreas center
Monika S Janot1, Orlin Belyaev, Sabine Kersting
1Department of General and Visceral Surgery, St. Josef Hospital, Ruhr University of Bochum, Bochum, Germany.
Background:
This study aimed to analyse the most common current indications for total pancreatectomy (TP) at a high-volume pancreas center.
Method:
Prospectively collected data on indications and short-term outcome of all TP's performed from January 2004 until June 2008 were analysed.
Results:
The total pancreatectomies (TP) were 63, i.e., 6.7% of all pancreatic procedures (n = 948). Indications for TP were classified into 4 groups: tumors of advanced stage, n = 23 (36.5%), technical problems due to soft pancreatic tissue, n = 18 (28.6%), troubles due to perioperative surgical complications, n = 15 (23.8%), and therapy-resistant pain due to chronic pancreatitis, n = 7 (11.1%). Surgical complications occurred in 23 patients (36.5%). The mortality in elective TP was 6.25%. Median postoperative stay was 21 days. Mortality, morbidity and the other perioperative parameters differed substantially according to the indication for pancreatectomy.
Conclusion:
Total pancreatectomy is definitely indicated for a limited range of elective and emergency situations. Indications can be: size or localisation of pancreatic tumor, trouble, technical diffuculties and therapy-refractory pain in chronic pancreatitis. A TP due to perioperative complications (troubles) after pancreatic resections is doomed by extremely high morbidity and mortality and should be avoided.
