Related Experiment Video
Updated: Jun 10, 2026
04:57
Controlled Reversible Visceral Arterial Ischemia, Venous Congestion and Combined Malperfusion via Midline Laparotomy in Rats
Published on: July 5, 2024
Colon ischemia: recent insights and advances
Paul Feuerstadt1, Lawrence J Brandt
1Division of Gastroenterology, Montefiore Medical Center, 111 East 210th Street, Bronx, NY 10467, USA. pfmets@yahoo.com
Current Gastroenterology Reports
|August 7, 2010
Summary
Ischemic colitis, a common gastrointestinal issue, involves hypoperfusion and reperfusion injury. Right-sided colon involvement presents uniquely with a worse prognosis, impacting treatment strategies.
Area of Science:
- Gastroenterology
- Vascular Medicine
Background:
- Ischemic colitis is the most frequent gastrointestinal manifestation of ischemic injury.
- Causes are diverse, involving local hypoperfusion and reperfusion.
- Injury spectrum ranges from reversible colopathy to fulminant colitis.
Purpose of the Study:
- To summarize the current understanding of ischemic colitis.
- To highlight the significance of lesion location on prognosis.
- To outline diagnostic and therapeutic approaches.
Main Methods:
- Review of existing literature on ischemic colitis.
- Analysis of clinical presentation, diagnosis, and outcomes.
- Correlation of disease location with prognosis.
Main Results:
- Ischemic colitis presents with varied injury patterns and typically segmental distribution.
- Isolated right colon involvement shows distinct presentation and poorer outcomes.
- Diagnosis relies on clinical suspicion, imaging, and colonoscopy.
Conclusions:
- Ischemic colitis encompasses a spectrum of colonic injury due to hypoperfusion/reperfusion.
- Right-sided colonic involvement signifies a worse prognosis.
- Most cases resolve with conservative care; severe cases may need surgery.
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