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Pore Size Distribution

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In concrete, the pore size distribution significantly influences the material's properties. Capillary pores, markedly larger than gel pores, form a vast network within partially hydrated cement paste, reducing the concrete's strength and increasing its permeability. This heightened permeability leads to a greater risk of damage from environmental factors like freeze-thaw cycles and chemical attacks, with the extent of vulnerability also being tied to the water-to-cement ratio.
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Related Experiment Video

Updated: Jun 10, 2026

Fabricating Superhydrophobic Polymeric Materials for Biomedical Applications

Fabricating Superhydrophobic Polymeric Materials for Biomedical Applications

Published on: August 28, 2015

Large-pore PDS mesh compared to small-pore PG mesh.

J Otto¹, M Binnebösel, S Pietsch

¹Department of Surgery, University Clinic RWTH Aachen, Pauwelsstrasse, Aachen, Germany. jeotto@ukaachen.d

Journal of Investigative Surgery : the Official Journal of the Academy of Surgical Research

|August 10, 2010

Summary

A new polydioxanone (PDS) mesh offers improved elasticity and fluid drainage compared to polyglycolic acid (PG) meshes for temporary abdominal closure, reducing inflammation and fibrosis.

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Published on: February 12, 2013

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Last Updated: Jun 10, 2026

Fabricating Superhydrophobic Polymeric Materials for Biomedical Applications

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Published on: August 28, 2015

Elastomeric PGS Scaffolds in Arterial Tissue Engineering

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Published on: April 8, 2011

Density Gradient Multilayered Polymerization (DGMP): A Novel Technique for Creating Multi-compartment, Customizable Scaffolds for Tissue Engineering

Density Gradient Multilayered Polymerization (DGMP): A Novel Technique for Creating Multi-compartment, Customizable Scaffolds for Tissue Engineering

Published on: February 12, 2013

Area of Science:

Biomaterials Science
Surgical Innovation
Tissue Engineering

Background:

Absorbable meshes are crucial for temporary abdominal closure after laparostoma.
Existing polyglycolic acid (PG) meshes exhibit limited elasticity and impede fluid drainage.
A novel polydioxanone (PDS) mesh with enhanced porosity and degradation profile was developed.

Purpose of the Study:

To evaluate the tissue response to a new PDS mesh compared to a PG mesh.
To assess the PDS mesh's suitability as an absorbable abdominal wall replacement.

Main Methods:

Implantation of PDS and PG meshes in rat abdominal walls for 7, 21, and 90 days.
Histological analysis including HE staining and immunohistochemistry (TUNEL, Ki67, TNF-R2, MMP-2, YB1, FVIII, gas6, AXL).
Quantification of granuloma size, cell turnover, apoptosis, neovascularization, and nerve ingrowth.

Main Results:

PDS mesh demonstrated attenuated inflammatory and fibrotic reactions compared to PG mesh.
Smaller granuloma size, reduced cell turnover, and less remodeling (apoptosis, MMP-2, TNF-R2) observed with PDS.
Increased neovascularization and nerve ingrowth were noted in the PDS mesh group.

Conclusions:

Monofilament PDS meshes can be engineered to minimize inflammatory and fibrotic responses.
The PDS mesh preserves elasticity and facilitates intra-abdominal fluid drainage.
This PDS mesh represents a promising alternative for temporary abdominal closure.