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Related Concept Videos

Bone Formation by Intramembranous Ossification01:29

Bone Formation by Intramembranous Ossification

Intramembranous ossification is one of the two processes involved in the development of bones within an embryo. The flat bones of the face, most of the cranial bones, and the clavicles are formed via this process. During intramembranous ossification, the bones develop directly from sheets of undifferentiated mesenchymal connective tissue.
The process begins when mesenchymal cells in the embryonic skeleton gather together and differentiate into osteogenic cells, which then develop into...
Bone Cells and Tissue01:30

Bone Cells and Tissue

Bones contain a relatively small number of cells entrenched in a matrix of organic and inorganic components. Although bone cells compose only a small amount of the bone volume, they are crucial to its function. Four types of cells are found within the bone tissue— osteoblasts, osteocytes, osteogenic cells, and osteoclasts.
Osteoblasts and Osteocytes
The osteoblast is the bone cell responsible for forming new bone tissue. It is found in the growing portions of bone, including the periosteum and...
Osteoclasts in Bone Remodeling01:31

Osteoclasts in Bone Remodeling

Osteoclasts are cells responsible for bone resorption and remodeling. They originate from hematopoietic progenitor cells present in the bone marrow. Numerous progenitor cells fuse to form multinucleated cells, each with 10-20 nuclei. A single osteoclast has a diameter of 150 to 200 µM. These cells have ruffled borders that break down the underlying bone tissue and release minerals such as calcium into the blood in bone resorption. Osteoclasts cling to bones with their ruffled edges during bone...
Bone Remodeling01:40

Bone Remodeling

Bone remodeling is a continuous and balanced process of bone resorption by osteoclasts and bone formation by osteoblasts. In adults, it helps maintain bone mass and calcium homeostasis. While mechanical stress can stimulate turnover as part of the normal maintenance and reparative process, several hormones also regulate bone remodeling.
Bone Formation by Endochondral Ossification01:24

Bone Formation by Endochondral Ossification

Bone formation, or ossification, begins around the sixth to seventh week of embryonic development. Most bones develop from a cartilaginous template through the process of endochondral ossification. Cartilage formation begins when clusters of mesenchymal cells differentiate into chondrocytes. These chondrocytes proliferate rapidly and secrete an extracellular matrix that becomes encased in a membrane called the perichondrium. The resulting cartilage model provides a template that resembles the...
Compact Bone01:27

Compact Bone

Most bones contain compact and spongy osseous tissue, but their distribution and concentration vary based on the bone's overall function.
Compact bone, also called cortical bone, is the denser, stronger of the two types of bone tissue. It is found under the periosteum and in the diaphyses of long bones, where it provides support and protection. The microscopic structural unit of compact bone is called an osteon, or haversian system. Each osteon is composed of concentric rings of calcified...

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Related Experiment Video

Updated: Jun 10, 2026

Stabilizing a Femur Osteotomy with a Plate Fixation in Ambystoma mexicanum
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Published on: April 12, 2024

Hamatum osteoblastoma.

F Gdoura1, M Trigui, Z Ellouze

  • 1Department of Orthopaedic Surgery, Traumatology, Habib Bourguiba Teaching Medical Center and Sfax Faculty of Medicine, el Aïn Higway km 0.5, 3029 Sfax, Tunisia.

Orthopaedics & Traumatology, Surgery & Research : OTSR
|August 10, 2010
PubMed
Summary

Osteoblastoma of the hamate bone is rare. Successful treatment was achieved through curettage, a conservative approach for this benign but potentially aggressive bone tumor.

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Area of Science:

  • Orthopedic Surgery
  • Oncology
  • Pathology

Background:

  • Osteoblastomas are rare benign bone tumors that can exhibit aggressive behavior.
  • Diagnosis often requires pathological examination due to non-specific clinical and radiological findings.
  • Carpal bone osteoblastomas are exceptionally infrequent, with limited documented cases.

Observation:

  • This report details a rare case of osteoblastoma occurring in the hamate bone.
  • The patient presented with symptoms necessitating diagnosis and treatment.
  • Initial clinical and radiological assessments were inconclusive, highlighting the need for definitive pathological analysis.

Findings:

  • The osteoblastoma of the hamate bone was successfully treated with curettage.
  • Pathological examination confirmed the diagnosis of osteoblastoma.
  • This case adds to the limited literature on osteoblastomas in carpal bones.

Implications:

  • Curettage represents a viable conservative treatment option for osteoblastoma of the hamate.
  • Radical resection may be reserved for recurrent or aggressive tumor forms, considering potential functional deficits.
  • Further research into the management of rare bone tumors in the carpal region is warranted.