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Updated: Jun 10, 2026

Refined Murine Model of Idiopathic Pulmonary Fibrosis
Published on: June 17, 2025
Pulmonary manifestations of the idiopathic inflammatory myopathies
Meena Kalluri1, Chester V Oddis
1Division of Pulmonary Medicine, University of Alberta, Edmonton, Canada. meenakalluri@med.ualberta.ca
Abstract:
Pulmonary involvement in myositis includes interstitial lung disease (ILD), respiratory muscle weakness, aspiration, infections, and drug-induced disease. ILD may precede myositis, and results in increased morbidity and mortality rates. Initial evaluation should include pulmonary function tests and high-resolution computed tomography. Nonspecific interstitial pneumonia (NSIP) is the most common histologic pattern on lung biopsy. Treatment usually consists of a combination of steroids and other immunosuppressive agents, and the response depends on the clinical presentation and underlying histology.
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