Related Experiment Video
Updated: Jun 10, 2026

Left Atrial Stenosis Induced Pulmonary Venous Arterialization and Group 2 Pulmonary Hypertension in Rat
Published on: November 18, 2018
The pulmonary vasculitides
Stephen K Frankel1, David Jayne
1National Jewish Health, Denver, CO 80206, USA. frankels@NJHealth.org
Abstract:
The vasculitides represent a spectrum of disorders characterized by inflammation and destruction of the blood vessel wall, and these entities commonly affect the respiratory system. Although challenging to diagnose and manage, recent advances in the treatment of these disorders has greatly improved the prognosis for patients with vasculitis, and with the advent of increasingly less toxic therapies, the future for these patients is brighter still.
Related Concept Videos
Pulmonary Hypertension: Classification and Pathogenesis
There are various classifications for PH, each relating to different underlying causes and also...
Pulmonary Embolism I: Introduction
Pulmonary Embolism I: Introduction
Other Pulmonary Disorders
Pulmonary Edema II: Pathophysiology
Treatment for Pulmonary Arterial Hypertension: Prostacyclin Receptor Agonists
These agonists bind to the IPR receptor situated on the plasma membrane of the pulmonary artery smooth muscle cells. This binding triggers a cascade of reactions known as the GS-AC-cAMP-PKA pathway. This pathway results in the relaxation of smooth muscle...

