Related Experiment Video
Updated: Jun 10, 2026

A Protocol for Computer-Based Protein Structure and Function Prediction
Published on: November 3, 2011
RefProtDom: a protein database with improved domain boundaries and homology relationships
Mileidy W Gonzalez1, William R Pearson
1Department of Biological Sciences, University of Maryland Baltimore County, Baltimore, MD 21250, USA. miledywgonzalez@gmail.com
Unlabelled:
RefProtDom provides a set of divergent query domains, originally selected from Pfam, and full-length proteins containing their homologous domains, with diverse architectures, for evaluating pair-wise and iterative sequence similarity searches. Pfam homology and domain boundary annotations in the target library were supplemented using local and semi-global searches, PSI-BLAST searches, and SCOP and CATH classifications.
Availability:
RefProtDom is available from http://faculty.virginia.edu/wrpearson/fasta/PUBS/gonzalez09a.
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