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Related Concept Videos

In Vitro Fertilization01:24

In Vitro Fertilization

In vitro fertilization (IVF) is a form of assisted reproductive technology where an egg is fertilized with sperm in a controlled laboratory environment before transferring the resulting embryo into the uterus. This process is designed to help individuals and couples experiencing difficulties conceiving.
The IVF process begins with ovarian stimulation, during which reproductive endocrinologists prescribe hormonal medications to stimulate the ovaries to produce multiple eggs instead of the single...
Cryo-electron Microscopy01:28

Cryo-electron Microscopy

Conventional electron microscopy (EM) involves dehydration, fixation, and staining of biological samples, which distorts the native state of biological molecules and results in several artifacts. Also, the high-energy electron beam damages the sample and makes it difficult to obtain high-resolution images. These issues can be addressed using cryo-EM, which uses frozen samples and gentler electron beams. The technique was developed by Jacques Dubochet, Joachim Frank, and Richard Henderson, for...
Meiosis II01:57

Meiosis II

Meiosis II is the second and final stage of meiosis. It relies on the haploid cells produced during meiosis I, each of which contain only 23 chromosomes—one from each homologous initial pair. Importantly, each chromosome in these cells is composed of two joined copies, and when these cells enter meiosis II, the goal is to separate such sister chromatids using the same microtubule-based network employed in other division processes. The result of meiosis II is two haploid cells, each containing...

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Related Experiment Video

Updated: Jun 10, 2026

Modified MicroSecure Vitrification: A Safe, Simple and Highly Effective Cryopreservation Procedure for Human Blastocysts
09:35

Modified MicroSecure Vitrification: A Safe, Simple and Highly Effective Cryopreservation Procedure for Human Blastocysts

Published on: March 2, 2017

Vitrification technology in whole embryo freezing.

Xiaodong Xie1, Lian Zou, Yang Shen

  • 1Maternal and Child Health Care Hospital, Nanjing Medical University, Wuxi Jiangsu 214002, China. xxd3100@163.com

Zhong Nan Da Xue Xue Bao. Yi Xue Ban = Journal of Central South University. Medical Sciences
|August 10, 2010
PubMed
Summary

Whole embryo vitrification freezing and thawed frozen embryo transplantation shows promising clinical outcomes. This efficient technology is a feasible option for patients undergoing assisted reproductive procedures, warranting further clinical investigation.

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Related Experiment Videos

Last Updated: Jun 10, 2026

Modified MicroSecure Vitrification: A Safe, Simple and Highly Effective Cryopreservation Procedure for Human Blastocysts
09:35

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Published on: March 2, 2017

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08:28

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Published on: February 28, 2019

Cryopreservation of Mouse Embryos by Ethylene Glycol-Based Vitrification
06:00

Cryopreservation of Mouse Embryos by Ethylene Glycol-Based Vitrification

Published on: November 18, 2011

Area of Science:

  • Reproductive Medicine
  • Embryology
  • In Vitro Fertilization (IVF)

Background:

  • Assisted reproductive technologies (ART) aim to improve pregnancy rates.
  • Embryo cryopreservation is a key component of ART, allowing for future transfers.
  • Vitrification offers a rapid cooling method for embryo preservation.

Purpose of the Study:

  • To evaluate the clinical outcomes of whole embryo vitrification freezing followed by thawed frozen embryo transplantation.
  • To compare these outcomes with fresh embryo transfer cycles.
  • To determine the clinical value of vitrification technology in conjunction with embryo recovery transplantation.

Main Methods:

  • A cohort of 40 patients undergoing whole embryo vitrification freezing was compared to 300 patients in a fresh in vitro fertilization and embryo transfer (IVF-ET) cycle.
  • Key parameters analyzed included the number of transferred embryos, high-quality embryos, endometrial thickness, estradiol (E₂) levels, and clinical pregnancy rates.

Main Results:

  • No significant differences were observed in the average number of transferred embryos, high-quality embryos, or endometrial thickness between the vitrification and fresh transfer groups.
  • Estradiol (E₂) levels were significantly higher in the fresh cycle group compared to the vitrification group (P<0.05).
  • The clinical pregnancy rate was significantly lower in the fresh cycle group than in the whole embryo vitrification group (P<0.05).

Conclusions:

  • Vitrification technology is presented as a simple, reliable, and efficient method for embryo freezing.
  • Whole embryo vitrification freezing and subsequent thawed frozen embryo transplantation is a feasible option for suitable patients.
  • The findings suggest the need for further clinical research to fully establish the benefits of this approach.