Related Experiment Video
Updated: Jun 10, 2026

Computer-Aided Three-Dimensional Visualization in the Treatment of Locally Advanced Thyroid Cancer
Published on: June 9, 2023
Successful treatment of a locally invasive cryptococcoma mimicking primary thyroid cancer with fluconazole
Evgenia Kagan1, Matthew B Madden, Chris H Parsons
1Department of Medicine, Hollings Cancer Center, Medical University of South Carolina, Charleston, 29425, USA.
Abstract:
A patient with no immune compromise and no constitutional or pulmonary symptoms presented with an enlarging neck mass abutting the thyroid gland and extending through the pleura into the lung. Microbiologic evaluation revealed a diagnosis of cryptococcoma, and the patient responded well to oral fluconazole therapy. To the authors' knowledge, this is the first case describing a locally invasive cryptococcoma mimicking a primary thyroid malignancy in the absence of systemic symptoms.

