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Related Experiment Videos

[High-dose methotrexate and hyperphenylalaninemia].

J L Dhondt1, J P Farriaux, F Millot

  • 1Laboratoire de Biochimie, Faculté Libre de Médecine, Lille, France.

Archives Francaises De Pediatrie
|April 1, 1991
PubMed
Summary
This summary is machine-generated.

High-dose methotrexate can transiently increase blood phenylalanine levels by affecting enzymes involved in its metabolism. This effect, though usually mild, may indicate broader enzyme inhibition, potentially causing neurological issues.

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Area of Science:

  • Biochemistry
  • Pharmacology
  • Neuroscience