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Related Concept Videos

DNA Microarrays02:34

DNA Microarrays

Microarrays are high-throughput and relatively inexpensive assays that can be automated to analyze large quantities of data at a time. They are used in genome-wide studies to compare gene or protein expression under two varied conditions, such as healthy and diseased states. Microarrays consist of glass or silica slides on which probe molecules are covalently attached through surface functionalization. Most commonly, the slides are prepared through the chemisorption of silanes to silica...
Pharmacogenomics: Identification of New Drug Targets01:29

Pharmacogenomics: Identification of New Drug Targets

Advances in genomics have profoundly influenced drug discovery by increasing both the speed and accuracy of pharmaceutical development. Pharmacogenomics, which examines how genetic variation influences drug response, facilitates the identification of novel therapeutic targets and enables patient stratification for personalized treatment. These strategies contribute to improved drug efficacy, minimized adverse effects, and more efficient clinical trial design.Mapping genetic differences...
Proteomics01:33

Proteomics

A proteome is the entire set of proteins that a cell type produces. We can study proteomes using the knowledge of genomes because genes code for mRNAs, and the mRNAs encode proteins. Although mRNA analysis is a step in the right direction, not all mRNAs are translated into proteins.
Proteomics is the study of proteomes' function. It involves the large-scale systematic study of the proteome to denote the protein complement expressed by a genome. Scientist Mark Wilkins coined the term proteomics...

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Related Experiment Video

Updated: Jun 10, 2026

Obtaining High-Quality Transcriptome Data from Cereal Seeds by a Modified Method for Gene Expression Profiling
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Obtaining High-Quality Transcriptome Data from Cereal Seeds by a Modified Method for Gene Expression Profiling

Published on: May 21, 2020

Microarray technology: a promising tool in nutrigenomics.

Andrea Masotti1, Letizia Da Sacco, Gian Franco Bottazzo

  • 1Bambino Gesù Children's Hospital, Research Institute (IRCCS), Rome, Italy.

Critical Reviews in Food Science and Nutrition
|August 10, 2010
PubMed
Summary

Microarray technology, applied to nutritional genomics (nutrigenomics), reveals how nutrients affect gene expression. This approach offers insights for improving diet, health, and developing new treatments for diseases like diabetes and cancer.

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DNA Microarrays: Sample Quality Control, Array Hybridization and Scanning
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DNA Microarrays: Sample Quality Control, Array Hybridization and Scanning

Published on: March 15, 2011

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Last Updated: Jun 10, 2026

Obtaining High-Quality Transcriptome Data from Cereal Seeds by a Modified Method for Gene Expression Profiling
07:18

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Published on: May 21, 2020

DNA Microarrays: Sample Quality Control, Array Hybridization and Scanning
09:27

DNA Microarrays: Sample Quality Control, Array Hybridization and Scanning

Published on: March 15, 2011

Area of Science:

  • Genomics
  • Molecular Biology
  • Nutritional Science

Background:

  • Microarray technology enables global gene expression profiling.
  • Understanding gene transcription regulation is crucial for various biological processes.
  • Nutritional genomics (nutrigenomics) investigates nutrient-genome interactions.

Purpose of the Study:

  • To review the clinical relevance of nutrition in disease management.
  • To propose microarray technology as a tool for nutrigenomic studies.
  • To explore the potential of nutrigenomics in improving health outcomes.

Main Methods:

  • Utilizing microarray technology for gene expression analysis.
  • Applying genomics and bioinformatics approaches in nutrigenomic research.
  • Reviewing existing literature on nutritional approaches to diseases.

Main Results:

  • Microarrays provide extensive data on gene expression markers and predictive factors.
  • Nutrigenomic studies using microarrays can identify how nutrients influence gene expression.
  • This technology aids in discovering novel natural agents for disease treatment.

Conclusions:

  • Microarray-based nutrigenomics holds promise for personalized nutrition and disease prevention.
  • The integration of microarrays into nutrigenomics can lead to improved dietary strategies.
  • Further research utilizing microarrays in nutrigenomics may uncover new therapeutic avenues for diseases like diabetes and cancer.