[New progress of related research of bone tissue engineering]

To review new progress of related research of bone tissue engineering in recent years.

Domestic and international literature concerning bone tissue engineering was reviewed and analyzed.

In the recent years, great progression had been made in the research and development of bone tissue engineering, it had been used in more and more hospitals, and relevant national regulations and protocols had been set up. As to seed cells of bone tissue engineering, autologous and allogeneic stem cells had been widely used, while recently embryonic stem cells and induced pluri potent stem cells had attracted most attentions. In the field of scaffolds materials, significant improvements had been made, from natural extractions to artificial polymers; from single construction to multiple compounds with surface modifications. As to the methods of construction, the static seeding approach had been widely accepted, and the applications of bioreactor had provided a stable and various micro-environment for the vitro-culture of different stem cells, which had been regarded as an alternative way of vitro-culture and construction for bone tissue engineering.

With the tremendous help of the techniques and approaches above, we shall expect a promising future of a new generation bone tissue engineering based medical products in the years to come.