Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Diabetic Retinopathy01:27

Diabetic Retinopathy

DefinitionDiabetic retinopathy is a microvascular complication of diabetes affecting the retinal blood vessels.Risk FactorsDiabetic retinopathy is present in almost all individuals with type 1 diabetes and more than 60% of those with type 2 diabetes after two decades of disease.The risk increases with poor glycemic control, hypertension, dyslipidemia, smoking, pregnancy, and puberty.Although cataracts and glaucoma are also more frequent in people with diabetes, retinopathy remains the leading...
Glaucoma: Overview01:25

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
Ischemic Stroke ll: Pathophysiology01:15

Ischemic Stroke ll: Pathophysiology

An ischemic stroke occurs when a cerebral blood vessel becomes obstructed, most often by a thrombus or embolus, interrupting the delivery of oxygen and glucose to brain tissue. Because neurons rely on continuous aerobic metabolism, energy failure begins within minutes of reduced perfusion. The region receiving the least blood flow becomes the infarct core, an area of irreversible cellular death. Surrounding this core lies the penumbra, a zone of hypoperfused but still viable tissue that is...
Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Photoreceptors and Visual Pathways01:22

Photoreceptors and Visual Pathways

At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category, whereas...
Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Genetic Testing in Inherited Retinal Disease: Current Strategies and Future Directions.

Journal of personalized medicine·2026
Same author

Visual Impairment and Cardiovascular Risk Factors in Hispanic and Latino Adults.

JAMA network open·2026
Same author

Quantitative Flavoprotein Fluorescence Parameters in Retinal and Optic Nerve Diseases: A Scoping Review.

Journal of clinical medicine·2026
Same author

Home Monitoring of Visual Functions in Neuro-Ophthalmic Diseases Using an AI-Assisted Virtual Reality Platform.

Journal of neuro-ophthalmology : the official journal of the North American Neuro-Ophthalmology Society·2026
Same author

Real-World Comparison of Overall Survival Among Patients With and Without Inherited Retinal Diseases.

Vision (Basel, Switzerland)·2026
Same author

Virtual Reality Visual Field Testing Reduces Visit Duration in a Neuro-Ophthalmology Clinic.

Current eye research·2026
Same journal

Longitudinal Structural and Functional Trajectories Following Netarsudil Intensification or Surgical Escalation in Primary Open-Angle Glaucoma.

Seminars in ophthalmology·2026
Same journal

Maternal Diabetes Mellitus During Pregnancy as a Risk Factor for Congenital Nasolacrimal Duct Obstruction in the Offspring - a Large-Scale National Study.

Seminars in ophthalmology·2026
Same journal

Clinical Spectrum and Genetics of Ocular Manifestations in Muscle Eye Brain Disease: A Literature Review.

Seminars in ophthalmology·2026
Same journal

Port Delivery System Vs Monthly Ranibizumab in VEGF-Driven Macular Disease: A Systematic Review and Meta-Analysis.

Seminars in ophthalmology·2026
Same journal

Genome Wide Pleiotropic Analysis Reveals Shared Genetic Architecture and Pathological Basis Between Retinitis Pigmentosa and Relevant Ocular Comorbidities.

Seminars in ophthalmology·2026
Same journal

Does QuantiFERON-Positive Tubercular Serpiginous-Like Choroiditis Affect Retinal and Choroidal Structures Differently in Affected Eyes Compared to Fellow Eyes and Healthy Controls? A Comparative OCT and OCT-A Study.

Seminars in ophthalmology·2026
See all related articles

Related Experiment Video

Updated: Jun 10, 2026

Rat Model of Photochemically-Induced Posterior Ischemic Optic Neuropathy
14:54

Rat Model of Photochemically-Induced Posterior Ischemic Optic Neuropathy

Published on: November 29, 2015

Ischemic optic neuropathy.

Alberto Gonzalez-Garcia1, Carlos E Mendoza-Santiesteban, Enrique A Mendoza-Santiesteban

  • 1The Institute of Neurology and Neurosurgery Dr. Rafael Estrada González, Havana, Cuba.

Seminars in Ophthalmology
|August 11, 2010
PubMed
Summary
This summary is machine-generated.

Anterior ischemic optic neuropathy (AION) is a common cause of vision loss in older adults. New optical coherence tomography findings may change how AION is managed in the future.

More Related Videos

The Rodent Model of Nonarteritic Anterior Ischemic Optic Neuropathy (rNAION)
06:49

The Rodent Model of Nonarteritic Anterior Ischemic Optic Neuropathy (rNAION)

Published on: November 20, 2016

System for Focal, Closed-System Central Nervous System Injury
04:02

System for Focal, Closed-System Central Nervous System Injury

Published on: November 29, 2024

Related Experiment Videos

Last Updated: Jun 10, 2026

Rat Model of Photochemically-Induced Posterior Ischemic Optic Neuropathy
14:54

Rat Model of Photochemically-Induced Posterior Ischemic Optic Neuropathy

Published on: November 29, 2015

The Rodent Model of Nonarteritic Anterior Ischemic Optic Neuropathy (rNAION)
06:49

The Rodent Model of Nonarteritic Anterior Ischemic Optic Neuropathy (rNAION)

Published on: November 20, 2016

System for Focal, Closed-System Central Nervous System Injury
04:02

System for Focal, Closed-System Central Nervous System Injury

Published on: November 29, 2024

Area of Science:

  • Ophthalmology
  • Neurology

Background:

  • Anterior ischemic optic neuropathy (AION) frequently causes vision loss in individuals over 50.
  • Understanding the pathophysiology of AION is crucial for effective patient management.

Purpose of the Study:

  • To explore the implications of optical coherence tomography (OCT) findings in anterior ischemic optic neuropathy.
  • To assess how new OCT information might influence future management strategies for AION.

Main Methods:

  • Review of current literature on AION.
  • Analysis of recent advancements in optical coherence tomography imaging techniques.
  • Correlation of OCT findings with clinical presentation and outcomes in AION patients.

Main Results:

  • Optical coherence tomography offers novel insights into the structural changes associated with AION.
  • Specific OCT parameters may predict disease progression or visual outcomes.
  • These findings suggest potential for earlier diagnosis and targeted interventions.

Conclusions:

  • OCT is a valuable tool for evaluating AION.
  • Emerging OCT data could lead to revised management protocols for anterior ischemic optic neuropathy.
  • Further research is warranted to integrate OCT into routine clinical practice for AION.