Quantitative proteomic approaches and their application in the study of yeast stress responses

The increasing popularity of proteomics has created a need for quantitative analysis methods. As a result, many different techniques are now available for performing gel-based or gel-free quantitative proteomic analysis of biological samples. These techniques provide an insight into global protein expression from identification to quantification, taking into account the highly dynamic status of the proteome. With its relatively small and compact genome, yeast is widely used as a model organism for molecular genetics, cell biology, and proteomic studies. In this review, we will show how quantitative proteomics has been used to study the effect of different stresses on yeast.