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[Left ventricular dysfunction measured in diabetic patients with chronic renal failure on continuous ambulatory

Gustavo Díaz-Arrieta1, María Elsa Mendoza-Hernández, Erika Pacheco-Aranda

  • 1Servicio de Medicina Interna, Centro Médico Nacional La Raza, Instituto Mexicano del Seguro Social, Distrito Federal, México. gustavodiazarrieta@yahoo.com

Revista Medica Del Instituto Mexicano Del Seguro Social
|August 11, 2010
PubMed

Insights

Diabetic patients with chronic renal failure on continuous ambulatory peritoneal dialysis (CAPD) frequently experience diastolic left ventricular dysfunction (95%) and systolic dysfunction (18.3%). Echocardiography revealed significant left ventricular hypertrophy in most patients.

Area of Science:

  • Cardiology
  • Nephrology
  • Diabetology

Context:

  • Diabetic patients with chronic renal failure (CRF) undergoing dialysis often develop left ventricular dysfunction.
  • Continuous ambulatory peritoneal dialysis (CAPD) is a common treatment for CRF.

Purpose:

  • To determine the prevalence of diastolic and systolic left ventricular dysfunction in diabetic patients with CRF treated with CAPD using echocardiography.

Summary:

  • The study examined 60 diabetic patients on CAPD. Echocardiography assessed left ventricular filling patterns (LVFP) and ejection fraction (LVEF). Results showed 91.7% had left ventricular concentric hypertrophy. Diastolic dysfunction was highly prevalent (95%), with 86.7% showing LVFP type I. Systolic dysfunction (LVEF < 0.55) was observed in 18.3% of patients.

Impact:

  • This study highlights the high prevalence of cardiac dysfunction in diabetic patients with CRF on CAPD, emphasizing the need for cardiac monitoring in this population.
  • Findings suggest that diabetic nephropathy and CAPD may contribute to significant cardiac remodeling and dysfunction.
Abstract

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