Related Experiment Video
Updated: Jun 10, 2026
Comprehensive Protocol to Sample and Process Bone Marrow for Measuring Measurable Residual Disease and Leukemic Stem Cells in Acute Myeloid Leukemia
Published on: March 5, 2018
Race and intensity of post-remission therapy in acute myeloid leukemia
Anna K Brady1, Alex Z Fu, Marc Earl
1Department of Hematologic Oncology and Blood Disorders, Cleveland Clinic Taussig Cancer Institute, Cleveland, OH, USA.
Background:
In many cancers, including AML, blacks have poorer overall survival. We investigated whether differences in post-remission therapy (PRT) were a contributing factor.
Methods:
We compared PRT cycle number and intensity and time to PRT in blacks and whites, among 460 patients with newly diagnosed AML.
Results:
Blacks and whites had PRT of equal cycle intensity and number, but black patients experienced a significant delay in starting PRT (2.73 months in blacks vs. 1 month in whites, p=0.047). Overall survival was equivalent in blacks and whites.
Conclusion:
PRT is delayed in blacks but does not explain differences in survival.
