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Updated: Jun 10, 2026

Synthesis of pH Dependent Pyrazole, Imidazole, and Isoindolone Dipyrrinone Fluorophores using a Claisen-Schmidt Condensation Approach
Published on: June 10, 2021
Synthesis, spectroscopic and structural study of trans- and
M G Bogdanov1, I V Svinyarov, B B Ivanova
1University of Sofia, St. Kl. Ohridsky, Department of Organic Chemistry, Sofia 1164, Bulgaria. BIvanova@chem.uni-sofia.bg
Abstract:
Synthesis, spectroscopic and structural study of trans- and cis-(±)-3-phenyl-4-(pyrrolidine-1-carbonyl)-isochroman-1-ones is performed in order to obtain the correlation between the crystal structure and spectroscopic properties of both isomers in solid-state. The methods such as single crystal X-ray diffraction, conventional and linear-polarized IR-spectroscopy, UV-spectroscopy, mass spectrometry, ¹H and ¹³C NMR are employed. Quantum chemical ab initio and DFT calculations are performed, to support the experimental data for the electronic structure and optical properties.
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