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Updated: Jun 10, 2026

A Model for Experimental Exposure of Humans to Larval Ixodes scapularis Ticks
Published on: December 1, 2023
Tickborne infections in the southern United States
Linda J Salinas1, Ronald A Greenfield, Susan E Little
1Infectious Diseases Section, Department of Medicine, University of Oklahoma College of Medicine, Oklahoma City, Oklahoma 73190, USA. linda-salinas@ouhsc.edu
Abstract:
Established and emerging tickborne infections are significant causes of human illness in the southern United States. Rocky Mountain spotted fever, human monocytic ehrlichiosis, human ewingii ehrlichiosis and tularemia are known pathogens in this geographic distribution. Rickettsia parkeri and novel ehrlichioses are more recently described tickborne infections reviewed in this article. An understanding of the tick vectors, pathogenesis, epidemiology, clinical presentation, diagnosis and treatment is useful for the clinician treating patients potentially infected with any of these pathogens. Prevention measures, the optimal method for removing an attached tick and current and future vaccine development conclude this review.
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