Related Experiment Videos
Molecular and cellular aspects of early B-cell development
1Max-Planck Institute for Immunobiology, Freiburg, FRG.
The molecular mechanisms underlying pre-B cell growth and immunoglobulin gene rearrangement have been actively investigated. Some growth factors for B-cell precursors as well as some genes activating V(D)J recombination have been identified. Furthermore, the molecular structure and signaling capacity of the surface immunoglobulin of pre-B cells have been characterized.
The molecular mechanisms underlying pre-B cell growth and immunoglobulin gene rearrangement have been actively investigated. Some growth factors for B-cell precursors as well as some genes activating V(D)J recombination have been identified. Furthermore, the molecular structure and signaling capacity of the surface immunoglobulin of pre-B cells have been characterized.