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Updated: Jun 10, 2026

Using En Face Immunofluorescence Staining to Observe Vascular Endothelial Cells Directly
Published on: August 20, 2019
The Gordon Wilson lecture. Understanding vascular endothelium: a pilgrim's progress. Endothelial dysfunction,
1Department of Pathology, Brigham and Women's Hospital, 75 Francis Street, Amory-3, Rm. 119, Boston, MA 02115, USA. mgimbrone@rics.bwh.harvard.edu
Abstract:
These are exciting times for the biomedical sciences, in general, and, in particular, for those who strive to understand the origins of complex human diseases, as we begin to focus with increasing precision on disease mechanisms at the cellular and molecular levels. Armed with the high-through-put technologies of the Post-Genomic Era, we now face the challenge of understanding biological systems at the level of their complex integration, and this will truly bring meaning to the concept of Systems Biology.
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