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Multimodal Volumetric Retinal Imaging by Oblique Scanning Laser Ophthalmoscopy (oSLO) and Optical Coherence Tomography (OCT)
Published on: August 4, 2018
Intraretinal segmentation on fourier domain optical coherence tomography
Jingjing Huang1, Xing Liu, Ziqiang Wu
1Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China.
Annals of the Academy of Medicine, Singapore
|August 11, 2010
Summary
Automated intraretinal segmentation using Fourier domain optical coherence tomography (OCT) provides reproducible retinal thickness measurements. Scan protocols influence results, highlighting the need for standardized methods in clinical applications.
Area of Science:
- Ophthalmology
- Medical Imaging
Background:
- Automated intraretinal segmentation using Fourier domain optical coherence tomography (OCT) is a developing area.
- Understanding retinal layer thickness is crucial for diagnosing and monitoring various eye conditions.
Purpose of the Study:
- To evaluate the reproducibility and comparability of automated intraretinal segmentation between radial and raster scan protocols on Fourier domain OCT.
- To assess macular thickness measurements derived from different scanning protocols.
Main Methods:
- Thirty normal subjects underwent OCT imaging using the RTVue-100 device.
- Both radial and raster scan protocols were applied three times per subject.
- Automated software performed intraretinal segmentation and provided macular thickness data.
Main Results:
- Both scanning protocols yielded reproducible measurements for inner, outer, and full retinal thickness.
- Raster scans provided slightly greater retinal thickness measurements than radial scans (P <0.05).
- Radial scans demonstrated marginally higher reproducibility.
Conclusions:
- Fourier domain OCT with automated segmentation is a valuable tool for studying retinal diseases.
- Variations in scanning protocols, devices, and data presentation methods complicate the establishment of normative values.
- Standardization is necessary for reliable clinical interpretation of OCT-derived retinal thickness.

