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Are new resuscitation guidelines better? Experience of an Asian metropolitan hospital
Shih Wen Hung1, Chien Chih Chen, Hsin Chin Shih
1Emergency Department, Shin-Kong Wu Ho-Su Memorial Hospital, Taipei, Taiwan.
Insights
New cardiopulmonary resuscitation (CPR) guidelines did not improve survival for out-of-hospital cardiac arrest (OHCA) patients in Asia. Increasing bystander CPR rates is crucial for improving OHCA survival.
Area of Science:
- Emergency Medicine
- Cardiology
- Public Health
Background:
- Cardiopulmonary resuscitation (CPR) guidelines were updated in 2005.
- The impact of these updated guidelines on out-of-hospital cardiac arrest (OHCA) survival in Asia remained unevaluated.
- This study assessed the effect of new CPR guidelines in an Asian metropolitan area.
Purpose of the Study:
- To evaluate the impact of implementing the 2005 CPR guidelines on OHCA patient survival.
- To identify factors influencing discharge survival among OHCA patients in an Asian city.
Main Methods:
- An observational cohort study compared OHCA patients before (Nov 2003-Oct 2005) and after (May 2006-Oct 2008) guideline implementation.
- Data collected using the Ustein style template.
- Statistical analysis included chi-squared tests, t-tests, and logistic regression.
Main Results:
- No significant benefits in recovery of spontaneous circulation (ROSC), survival-to-ICU, or survival-to-hospital discharge were observed after guideline implementation.
- Rates of ventricular fibrillation/pulseless VT, witnessed arrest, and bystander CPR were lower than in Western studies.
- Witnessed arrest and initial rhythm of VF/pulseless VT were independent predictors of discharge survival.
Conclusions:
- The 2005 CPR guidelines did not demonstrably improve OHCA survival rates in this Asian population.
- Factors independently associated with survival-to-hospital discharge were witnessed arrest and initial rhythm of VF/pulseless VT.
- Enhancing bystander CPR rates and training may be more impactful than frequent guideline revisions for improving OHCA survival in Asia.
Introduction:
Cardiopulmonary resuscitation (CPR) guidelines were revised in 2005 based on new evidence and expert consensus. However, the benefits of the new guidelines remain undetermined and their influence has not been published in Asia. This study aimed to evaluate the impact of implementing the new resuscitation guidelines and identify factors that influence the discharge survival of out-of-hospital cardiac arrest (OHCA) patients in an Asian metropolitan city.
Materials And Methods:
This was an observational cohort study of all OHCA patients seen by the emergency medical service during the period before (Nov 2003 to Oct 2005) and after (May 2006 to Oct 2008) implementing the new resuscitation guidelines. Detailed clinical information was recorded using the Ustein style template. Statistical analysis was done using X2 test or t-test for univariate analysis and the logistic regression model for multivariate analysis.
Results:
There were 463 patients before and 430 patients after the new guidelines who received resuscitation. The rate of recovery of spontaneous circulation (ROSC), survival-to-intensive care unit (ICU) admission, and survival-to-hospital discharge all showed no benefits regarding the new resuscitation guidelines (ROSC: 42% vs 39%, P = 0.32; Survival-to-ICU admission: 33% vs 30%, P = 0.27; survival-to-hospital discharge: 10% vs 7%, P = 0.09). The rate of ventricular fibrillation/pulseless ventricular tachycardia (VF/pulseless VT), rate of witnessed arrest, and rate of bystander CPR were much lower than in Western studies. After multivariate logistic regression, factors related to discharge survival were witnessed arrest and initial rhythm with VF/pulseless VT. The new resuscitation guidelines did not significantly influence the discharge survival.
Conclusions:
We did not observe any improvement in survival after implementing the new guidelines. Independent factors of survival-to-hospital discharge are witnessed arrest and initial rhythm with VF/pulseless VT. Because the rates of VF/pulseless VT and bystander CPR in Asia are low, popularising CPR training programmes and increasing the rate of bystander CPR may be more important for improving OHCA survival rates than frequent guideline changes.
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