Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

UV–Vis Spectroscopy of Conjugated Systems

UV–Vis Spectroscopy of Conjugated Systems

Organic compounds with conjugated double bonds show strong absorption features in the UV–visible region of the electromagnetic spectrum attributed to π&VeryThinSpace;→&VeryThinSpace;π* electronic excitations. Generally, a UV–vis absorption spectrum is recorded as a plot of absorbance vs wavelength. The wavelength of maximum absorbance, which manifests as a peak in the absorption spectrum, is denoted as λmax.
One of the factors influencing λmax is the extent of conjugation in the...

UV–Vis Spectroscopy: Molecular Electronic Transitions

UV–Vis Spectroscopy: Molecular Electronic Transitions

In Ultraviolet–Visible (UV–Vis) spectroscopy, the absorption of electromagnetic radiation is used to probe the electronic structure of molecules. This technique provides insights into molecular electronic transitions, particularly the movement of electrons between different molecular orbitals. Radiation is absorbed if the energy of the electromagnetic radiation passing through the molecule is precisely equal to the energy difference between the excited and ground states. During this process,...

2D NMR: Overview of Heteronuclear Correlation Techniques

2D NMR: Overview of Heteronuclear Correlation Techniques

Heteronuclear correlation spectroscopy is an analytical technique that investigates the coupling between different types of nuclei, often a proton and an X-nucleus, such as carbon-13 or nitrogen-15. This method is commonly used in nuclear magnetic resonance (NMR) spectroscopy to gain insights into complex chemical compounds' structural and compositional aspects. A typical heteronuclear correlation spectrum displays X-nucleus chemical shifts on one axis and a proton spectrum on the other axis.

2D NMR: Homonuclear Correlation Spectroscopy (COSY)

2D NMR: Homonuclear Correlation Spectroscopy (COSY)

Homonuclear correlation spectroscopy, or COSY, is a 2-dimensional NMR technique that provides information about coupled protons. Typically, the geminal and vicinal coupling are observed. For example, consider the COSY spectrum of ethyl acetate, where its 1D proton NMR spectrum is plotted along the vertical and horizontal axes with their corresponding chemical shift scale. Three spots on the diagonal corresponding to the three peaks in the 1D proton spectrum are called diagonal peaks. The COSY...

NMR Spectroscopy: Spin–Spin Coupling

NMR Spectroscopy: Spin–Spin Coupling

The spin state of an NMR-active nucleus can have a slight effect on its immediate electronic environment. This effect propagates through the intervening bonds and affects the electronic environments of NMR-active nuclei up to three bonds away; occasionally, even farther. This phenomenon is called spin–spin coupling or J-coupling. Coupling interactions are mutual and result in small changes in the absorption frequencies of both nuclei involved. While nuclei of the same element are involved in...

2D NMR: Overview of Homonuclear Correlation Techniques

2D NMR: Overview of Homonuclear Correlation Techniques

Homonuclear correlation spectroscopy (COSY) is a powerful technique used in Nuclear Magnetic Resonance (NMR) spectroscopy to study the correlations between nuclei of the same type within a molecule. It provides information about scalar couplings between adjacent nuclei, which helps determine connectivity and structural information. There are several COSY variants, each with its unique strengths and experimental parameters.
COSY90 is the standard two-dimensional (2D) COSY experiment that...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Ala-Ce@Ce6 hybrid supramolecular nanozyme for oxygen self-supplying hypoxia photodynamic therapy.

Biomaterials·2026

Same author

Clickable Universal Tumor-Antigen Equipping Strategy for Remedial Chimeric Antigen Receptor T Cells to Destroy Solid Tumors.

ACS nano·2026

Same author

A self-assembled HSA-ICG nanoprobe enables accurate photoacoustic thermometry and feedback-controlled tumor photothermal therapy.

Biomaterials science·2026

Same author

Cyanine-scaffold fluorogenic probes for visual detection of nitroreductase in living bacteria.

Journal of materials chemistry. B·2025

Same author

Highly Stable and Bright NIR-II AIE Dots for Fluorescence Imaging-Guided Photothermal Ablation of Endometriosis.

Advanced healthcare materials·2025

Same author

808 nm Light-Triggered Cyanine-Decorated Iridium(III) Complexes for Antibacterial Photodynamic Therapy in Deep-Tissue.

Inorganic chemistry·2025

Search research articles

Related Experiment Video

Updated: Jun 10, 2026

Resonance Raman Spectroscopy of Extreme Nanowires and Other 1D Systems

Resonance Raman Spectroscopy of Extreme Nanowires and Other 1D Systems

Published on: April 28, 2016

Crossed-nanowire molecular junctions: a new multispectroscopy platform for conduction--structure correlations.

Heayoung P Yoon¹, Masato M Maitani, Orlando M Cabarcos

¹Department of Electrical Engineering, The Pennsylvania State University, University Park, Pennsylvania 16802, USA.

|August 12, 2010

Summary

We developed a new platform for measuring molecular junctions, simultaneously analyzing electrical properties and vibrational spectra. This allows detailed study of molecular behavior and advanced phenomena in nanoscale devices.

More Related Videos

Silicon Nanowires and Optical Stimulation for Investigations of Intra- and Intercellular Electrical Coupling

Silicon Nanowires and Optical Stimulation for Investigations of Intra- and Intercellular Electrical Coupling

Published on: January 28, 2021

All-electronic Nanosecond-resolved Scanning Tunneling Microscopy: Facilitating the Investigation of Single Dopant Charge Dynamics

All-electronic Nanosecond-resolved Scanning Tunneling Microscopy: Facilitating the Investigation of Single Dopant Charge Dynamics

Published on: January 19, 2018

Related Experiment Videos

Last Updated: Jun 10, 2026

Resonance Raman Spectroscopy of Extreme Nanowires and Other 1D Systems

Resonance Raman Spectroscopy of Extreme Nanowires and Other 1D Systems

Published on: April 28, 2016

Silicon Nanowires and Optical Stimulation for Investigations of Intra- and Intercellular Electrical Coupling

Silicon Nanowires and Optical Stimulation for Investigations of Intra- and Intercellular Electrical Coupling

Published on: January 28, 2021

All-electronic Nanosecond-resolved Scanning Tunneling Microscopy: Facilitating the Investigation of Single Dopant Charge Dynamics

All-electronic Nanosecond-resolved Scanning Tunneling Microscopy: Facilitating the Investigation of Single Dopant Charge Dynamics

Published on: January 19, 2018

Area of Science:

Nanotechnology
Molecular Electronics
Spectroscopy

Background:

Understanding molecular behavior at the nanoscale is crucial for developing advanced electronic devices.
Simultaneous measurement of electrical and spectroscopic properties of single molecular junctions is challenging.

Purpose of the Study:

To report a novel crossed-nanowire platform for simultaneous characterization of molecular junctions.
To enable direct measurement of current-voltage-temperature (IVT) characteristics alongside inelastic electron tunneling (IET) and Raman vibrational spectra.

Main Methods:

Fabrication of a crossed-nanowire molecular junction array.
Simultaneous measurement of IVT characteristics, IET, and Raman spectra on the same junction.
Utilizing dithiol-terminated oligo(phenylene-ethynylene) molecules for junction assembly.

Main Results:

Demonstrated simultaneous acquisition of electrical and spectroscopic data from single molecular junctions.
Showcased that both IET and Raman spectroscopy probe gap-confined molecules, revealing distinct molecular features.
Verified the platform's capability to investigate molecular switching and cooperative effects.

Conclusions:

The developed platform offers a versatile tool for in-depth investigation of molecular electronics.
This approach allows for scalable studies of junction geometries and array sizes.
Provides new insights into molecular phenomena at the single-molecule level.