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Updated: Jun 10, 2026

Label-free Single Molecule Detection Using Microtoroid Optical Resonators
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Nanoscale optical detector with single-photon and multiphoton sensitivity.

David Bitauld1, Francesco Marsili, Alessandro Gaggero

  • 1COBRA Research Institute, Eindhoven University of Technology, PO Box 513, 5600 MB Eindhoven, The Netherlands. david.bitauld@tyndall.ie

Nano Letters
|August 12, 2010
PubMed
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Researchers developed a novel nanoscale detector with single-photon sensitivity and nanosecond response. This device enables photon number mapping on the nanoscale, advancing nanophotonics research.

Area of Science:

  • Physics
  • Nanotechnology
  • Quantum Optics

Background:

  • Superconducting nanowire single-photon detectors (SNSPDs) offer high sensitivity and temporal resolution.
  • Current SNSPDs lack subwavelength spatial resolution, limiting nanoscale investigations.
  • There is a need for nanoscale detectors capable of resolving photon number statistics.

Purpose of the Study:

  • To introduce the first nanoscale detector with single-photon sensitivity and nanosecond response time.
  • To demonstrate the capability of this nanodetector for multiphoton detection and photon number statistics mapping.
  • To integrate the high temporal resolution of SNSPDs with subwavelength spatial resolution.

Main Methods:

  • Fabrication of nanoscale detectors with dimensions down to approximately 50 x 50 nm^2.

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Last Updated: Jun 10, 2026

Label-free Single Molecule Detection Using Microtoroid Optical Resonators
08:53

Label-free Single Molecule Detection Using Microtoroid Optical Resonators

Published on: December 29, 2015

Optical Trapping of Nanoparticles
13:39

Optical Trapping of Nanoparticles

Published on: January 15, 2013

Biomolecular Imaging of Cellular Uptake of Nanoparticles using Multimodal Nonlinear Optical Microscopy
07:13

Biomolecular Imaging of Cellular Uptake of Nanoparticles using Multimodal Nonlinear Optical Microscopy

Published on: May 16, 2022

  • Utilizing the hot-spot formation principle in superconducting nanowires.
  • Operation in both single-photon and multiphoton detection modes with adjustable thresholds (N=1-4 photons).

    • Main Results:

    • Achieved nanoscale detection with dimensions as small as 50 x 50 nm^2.
    • Demonstrated single-photon sensitivity with a nanosecond response time.
    • Successfully operated the detector in multiphoton mode, enabling photon number discrimination and statistics mapping.

    Conclusions:

    • The developed nanodetector bridges the gap between SNSPD performance and subwavelength resolution.
    • This technology offers a powerful tool for studying nanophotonic devices at low temperatures.
    • Potential applications include advanced quantum optics experiments and nanoscale imaging.