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Candidate Gene Testing in Clinical Cohort Studies with Multiplexed Genotyping and Mass Spectrometry
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Asthma-susceptibility variants identified using probands in case-control and family-based analyses

Blanca E Himes1, Jessica Lasky-Su, Ann C Wu

  • 1Harvard-MIT Division of Health Sciences and Technology, Cambridge, MA, USA.

BMC Medical Genetics
|August 12, 2010
PubMed
Summary

Researchers identified a novel single nucleotide polymorphism (SNP) associated with asthma by combining family-based and case-control study designs. This approach enhances the discovery of genetic variants for complex diseases like asthma.

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