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Updated: Jun 10, 2026
08:20
MRI-guided dmPFC-rTMS as a Treatment for Treatment-resistant Major Depressive Disorder
Published on: August 11, 2015
[Migraine and depression should be treated concurrently].
Mark A Louter1, Gerthe Veen, Michel D Ferrari
1Leids Universitair Medisch Centrum, Afd. Neurologie, Leiden, the Netherlands. m.a.louter@lumc.nl
Nederlands Tijdschrift Voor Geneeskunde
|August 12, 2010
Summary
Migraine and depression frequently co-occur, increasing risks for both conditions. Early recognition and collaborative specialist care are crucial for managing this complex comorbidity.
Area of Science:
- Neurology
- Psychiatry
- Epidemiology
Context:
- Migraine and depression are prevalent, interconnected disorders.
- A bidirectional relationship exists, where each condition elevates the risk of developing the other.
- The chronification of migraine exacerbates depression risk, and vice versa.
Purpose:
- To highlight the significant comorbidity between migraine and depression.
- To underscore the role of common pathophysiological mechanisms.
- To emphasize the impact of medication misuse on chronic migraine and associated depression.
Summary:
- Migraine patients face a higher likelihood of depression, and depressed individuals are more prone to migraines.
- The progression to chronic migraine is linked to medication overuse, further increasing depression risk.
- Understanding this complex interplay is vital for effective patient management.
Impact:
- Alerts general practitioners, psychiatrists, and neurologists to the dual diagnosis.
- Recommends multidisciplinary specialist involvement for accurate diagnosis and treatment.
- Improves patient outcomes through integrated care approaches for comorbid migraine and depression.
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