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Updated: Jun 10, 2026

Microsurgical Clip Obliteration of Middle Cerebral Aneurysm Using Intraoperative Flow Assessment
Published on: September 25, 2009
[Sylvius (1614-1672) and his fissure]
Jan van Gijn1, Joost P Gijselhart
1Nederlands Tijdschrift voor Geneeskunde, Amsterdam, the Netherlands. jan@vangijn.com
Abstract:
Franciscus dele Boë, or Sylvius, was born into a family of French Huguenots who had moved to the province of Hessen. He studied medicine in Sedan, Leiden and Basle. He was a private teacher in anatomy in Leiden for some years, and while teaching he drew the attention of his students to the long fissure on either side of the cerebral surface. He practised successfully as a physician in Amsterdam from 1641 onwards, until he was recalled to the chair of medicine in Leiden in 1658. He emphasized the role of chemical processes in the human body (iatrochemistry).
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