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Related Experiment Video

Updated: Jun 10, 2026

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

3D-Neuronavigation In Vivo Through a Patient's Brain During a Spontaneous Migraine Headache

Published on: June 2, 2014

[Preventive treatment for migraine].

Wim M Mulleners¹, Joost Haan, Frans Dekker

¹Canisius-Wilhelmina Ziekenhuis, afd. Neurologie, Nijmegen, the Netherlands. w.mulleners@cwz.nl

Nederlands Tijdschrift Voor Geneeskunde

|August 12, 2010

Summary

This summary is machine-generated.

Preventive treatment for migraine is recommended for patients with frequent attacks. While current medications offer some relief, their effectiveness and side effects vary, necessitating careful individual adjustment.

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Area of Science:

Neurology
Pharmacology

Context:

Migraine management guidelines recommend preventive treatment for patients averaging two or more attacks monthly.
Treatment decisions also consider attack duration, severity, and response to acute therapies.

Purpose:

To outline criteria for initiating preventive migraine treatment.
To discuss the efficacy, limitations, and side effects of current preventive medications.

Summary:

Preventive treatment is indicated for frequent migraines, with decisions informed by attack frequency, duration, severity, and acute treatment response.
Currently available preventive drugs (e.g., beta-blockers, sodium valproate, topiramate, candesartan) were repurposed from other therapeutic areas.
Approximately 50% of patients experience a 50% reduction in attack frequency, with potential for reduced severity; however, unpredictable individual responses and side effects are common.
Cardiovascular drugs are frequently used, and careful medication adjustment is crucial for patients with comorbid cardiovascular or pulmonary conditions.

Impact:

Highlights the need for personalized treatment strategies in migraine prevention.
Underscores the challenges associated with current preventive therapies, including variable efficacy and tolerability.
Emphasizes the importance of considering comorbidities when selecting preventive migraine medications.