Germline modification using mouse spermatogonial stem cells

Related Experiment Video

Updated: Jun 10, 2026

Application of Mouse Parthenogenetic Haploid Embryonic Stem Cells as a Substitute of Sperm
08:08

Application of Mouse Parthenogenetic Haploid Embryonic Stem Cells as a Substitute of Sperm

Published on: November 19, 2020

Mito Kanatsu-Shinohara1, Takashi Shinohara

  • 1Department of Molecular Genetics, Graduate School of Medicine, Kyoto University, Kyoto, Japan.

Methods in Enzymology
|August 12, 2010
PubMed

More Related Videos

Mouse Round Spermatid Injection08:41

Mouse Round Spermatid Injection

Published on: January 26, 2024

Serial Enrichment of Spermatogonial Stem and Progenitor Cells (SSCs) in Culture for Derivation of Long-term Adult Mouse SSC Lines12:26

Serial Enrichment of Spermatogonial Stem and Progenitor Cells (SSCs) in Culture for Derivation of Long-term Adult Mouse SSC Lines

Published on: February 25, 2013

Related Concept Videos

In-vitro Mutagenesis01:16

In-vitro Mutagenesis

To learn more about the function of a gene, researchers can observe what happens when the gene is inactivated or “knocked out,” by creating genetically engineered knockout animals. Knockout mice have been particularly useful as models for human diseases such as cancer, Parkinson’s disease, and diabetes.
Spermatogenesis01:41

Spermatogenesis

Spermatogenesis is the process by which haploid sperm cells are produced in the male testes. It starts with stem cells located close to the outer rim of seminiferous tubules. These spermatogonial stem cells divide asymmetrically to give rise to additional stem cells (meaning that these structures “self-renew”), as well as sperm progenitors, called spermatocytes. Importantly, this method of asymmetric mitotic division maintains a population of spermatogonial stem cells in the male reproductive...