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Microfluidics in Assessing Platelet Function
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Published on: November 8, 2024

[Significance of platelet function tests]

Z Wolf1, H Mani, E Lindhoff-Last

  • 1Medizinische Klinik III, Schwerpunkt Angiologie und Hämostaseologie, Klinikum der Johann Wolfgang Goethe-Universität, Theodor-Stern-Kai 7, 60590, Frankfurt am Main, Deutschland. Zsuzsanna.Wolf@kgu.de

Der Internist
|August 12, 2010
PubMed

Numerous laboratory tests are in use to detect congenital or acquired platelet function disorders. Platelet aggregometry, using ADP, collagen, arachidonic acid or ristocetin as inductor is the standard test system for diagnosis. It is also used to detect platelet non-response to antiplatelet therapy. Studies have demonstrated that laboratory assessment of platelet non response to aspirin or clopidogrel is associated with adverse outcomes, and they indicate the importance of adjusting antiplatelet therapy in patients with a low degree of platelet inhibition. Nevertheless, a standardized method for identifying these patients is still missing.

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