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Updated: Jun 10, 2026

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
[Effect of cpap therapy on sleep quality in patients with OSAS]
Verona Mihai1, Gianina Rusu, Tr Mihăescu
1Spitalul Clinic de Pneumologie Iaşi, Universitatea de Medicină şi Farmacie Gr.T. Popa Iaşi, Facultatea de Medicină.
Unlabelled:
For an adequate analysis of sleep quality was assessed a new composed index wich objectively approached variate polisomnographic parameters. We used this new concept--sleep disturbances index-SDI in patients with obstructive sleep apnea (OSAS), before and after the beginning of CPAP therapy.
Material And Method:
41 patients were evaluated and for each one we calculated SDI score. All patients were split in two groups according with apnea-hipopnea index (AHI), and we correlated SDI with AHI as marker of severity of the disease and with Epworth Sleepiness Scale's scores, as an subjective evaluation. After 1 month of CPAP therapy, SDI was reevaluated.
Results:
SDI is correlating with the severity of the disease: for group 1, with 5 < AHI < 15, SDI= 2.24 +/- 0.88, r = 0.53, p < 0.01 and for group 2, with AHI >15, SDI = 3.23 +/- 0.69, p < 0.01, r = 0.46. There was no significant correlation between SDI and ESS scores (r = 0.23, p < 0.01). SDI lowers significant during CPAP therapy: SDI= 1.48 +/- 0.60, respectiv SDI = 1.90 +/- 1.23.
Conclusion:
The severity of OSAS is correlated with increased SDI, but can be seen interindividual variability. The effect of CPAP therapy is reflecting also in sleep quality.
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