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Updated: Jun 10, 2026

Assessment of Maternal Vascular Remodeling During Pregnancy in the Mouse Uterus
Published on: December 5, 2015
[Agnogenic myeloid metaplasia in pregnancy. Case report]
Iuliana Manole1, Gh Costăchescu, Marie Jeanne Aldea
1Universitatea de Medicină şi Farmacie Gr.T. Popa Iaşi Facultatea de Medicină, Disciplina de Obstetrică-Ginecologie.
Unlabelled:
Idiopathic myelofibrosis is a rare myeloproliferative disorder characterized by excessive accumulation of connective tissue in the bone marrow in association with anemia, splenomegaly and extramedullary hematopoiesis. A rare case of pregnancy in a patient with agnogenic myeloid metaplasia who carried a term pregnancy is described. In spite of the increased perinatal risks, a favorable outcome was possible with close antepartum surveillance.
Conclusion:
Idiopathic myelofibrosis was once thought to be a contraindication to pregnancy. With careful management, successful pregnancies can be achieved.
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