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Updated: Jun 10, 2026

Combinatorial Synthesis of and High-throughput Protein Release from Polymer Film and Nanoparticle Libraries
Published on: September 6, 2012
[New polymer-drug systems based on natural and synthetic polymers]
Stefania Racoviţă1, Silvia Vasiliu, Liliana Foia
1Institutul de Chimie Macromoleculaă Petru Poni Iaşi, Universitatea de Medicină şi Farmacie Gr.T. Popa Iaşi, Facultatea de Medicină Dentară.
Abstract:
The great versatility of polymers makes them very useful in the biomedical and pharmaceutical fields. The combination of natural and synthetic polymers leads to new materials with tailored functional properties. The aim of this work consists in the preparation of new drug delivery system based on chitosan (natural polymer) and polybetaines (synthetic polymers), by a simple process, well known in the literature as complex coacervation methods. Also, the adsorption and release studies of two antibiotics as well as the preservation of their bactericidal capacities were performed.
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