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Are insulin resistance index, IGF-1 and metabolic syndrome components correlates with severe preeclampsia?
Edimárlei Gonsales Valério1, Ana Lúcia Letti Müller, Sérgio Hofmeister Martins-Costa
1Programa de Pós-Graduação em Medicina: Ciências Médicas, Faculdade de Medicina, Universidade Federal do Rio Grande do Sul, RS, Brazil. edimarleigv@terra.com.br
Objective:
Analyse the relation between insulin resistance and severe preeclampsia (SPE).
Methods:
Case control study paired by body mass index and gestational age; including 16 patients with severe SPE and 16 normotensive controls. Insulin resistance was assessed through the HOMA-IR and QUICKI-IS indexes.
Results:
There was no significant difference between the groups regarding the HOMA-IR and QUICKI-IS indexes and HDL cholesterol. Triglyceride levels were higher and the IGF-1 was lower in the SPE group than in the control group.
Conclusions:
There were no differences in the insulin resitance indexes between the group with SPE and normal controls.
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