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Cyclosporine-A therapy-induced multiple bilateral breast and accessory axillary breast fibroadenomas: a case report
Ahmed Darwish1, Ayman O Nasr, Lamya A El Hassan
1P,O, Box 102, Department of Surgery, Faculty of Medicine, University of Khartoum, Sudan. aomnasr@hotmail.com.
Introduction:
Breast adenoma is common. However, in the setting of post-transplantation immune suppression it may be expressed differently.
Case Presentation:
A 35-year-old Sudanese woman, with a history of renal transplantation two and half years prior to presentation, was on a single immune suppression therapy in the form of cyclosporine-A since the transplantation. During a regular follow-up visit, she was noticed to have gingival hypertrophy and bilateral breast and axillary swellings. She underwent successful surgical resection of the bilateral fibroadenomas.
Conclusions:
Cyclosporine-A therapy post renal transplantation is associated with an increased incidence of benign breast changes as fibroadenoma. Regular follow-up and appropriate selection of immunosuppressant therapy are essential in the post transplantation management of these patients.
