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Related Concept Videos

Clinical Significance of Antibiotic Resistance01:25

Clinical Significance of Antibiotic Resistance

Methicillin-resistant Staphylococcus aureus (MRSA) presents a critical public health threat, arising from its capacity to resist β-lactam antibiotics due to acquisition of the mecA gene within the staphylococcal cassette chromosome mec (SCCmec). This gene encodes penicillin-binding protein 2a (PBP2a), which impairs binding efficacy of methicillin and other β-lactams. MRSA has evolved into distinct clonal lineages impacting humans and animals alike, reinforcing its significance within the One...
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Toxoplasmosis

Toxoplasmosis, a zoonotic disease caused by the protozoan Toxoplasma gondii, poses significant public health challenges globally due to its high seroprevalence and varied clinical manifestations. As an obligate intracellular parasite, T. gondii can infect all warm-blooded vertebrates, but felids are its only definitive hosts, shedding unsporulated oocysts into the environment. Humans typically acquire the infection through ingestion of tissue cysts in undercooked meat or oocysts from...
Infectious Diseases and Their Occurrence01:28

Infectious Diseases and Their Occurrence

Infectious diseases appear in populations through various transmission patterns, influenced by pathogen characteristics, population immunity, environmental conditions, and social behavior. Understanding these patterns is essential for effective public health surveillance and intervention. These categories—sporadic, outbreak, epidemic, pandemic, and endemic—help frame the nature and scope of disease events.Sporadic diseases occur irregularly and infrequently, without a predictable temporal or...
Smallpox01:24

Smallpox

Smallpox is a severe contagious disease caused by the Variola major virus, a double-stranded DNA member of the Poxviridae family.Variola major transmission occurs primarily via inhalation of virus-laden droplets or direct contact with infectious scabs. The incubation period averages approximately seven days, although it may range from 7 to 17 days depending on the inoculum and host factors.Clinically, the prodromal phase is marked by an abrupt onset of high fever, malaise, headache, and myalgia.
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Bacterial Phylum Spirochaetes

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Microorganisms in Medicine and Therapeutics

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Related Experiment Video

Updated: Jun 10, 2026

Diagnosis and Surgical Treatment of Human Brucellar Spondylodiscitis
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Diagnosis and Surgical Treatment of Human Brucellar Spondylodiscitis

Published on: May 23, 2021

Brucellosis: past, present and future.

P Nicoletti1

  • 1College of Veterinary Medicine, University of Florida, Gainesville, FL, USA.

Prilozi
|August 13, 2010
PubMed
Summary

Widespread vaccination is the most effective method for controlling animal brucellosis (a global zoonosis), which in turn helps reduce human cases. Long-term commitment and international support are crucial for success, especially in developing nations.

Area of Science:

  • Veterinary Medicine
  • Public Health
  • Zoonotic Diseases

Background:

  • Brucellosis is a significant global zoonosis with complex biological and epidemiological characteristics.
  • Understanding its pathogenesis, diagnostics, and public health impact is crucial for effective control strategies.

Purpose of the Study:

  • To provide a comprehensive overview of brucellosis, covering its biology, epidemiology, pathogenesis, diagnostics, public health implications, and control measures.
  • To highlight the challenges and strategies for managing brucellosis as a global zoonotic threat.

Main Methods:

  • Review of existing literature and control strategies for brucellosis.
  • Emphasis on vaccination as a primary method for animal brucellosis control.
  • Discussion of public health aspects and the link between animal and human cases.

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Microscopy-based Assays for High-throughput Screening of Host Factors Involved in Brucella Infection of Hela Cells
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Microscopy-based Assays for High-throughput Screening of Host Factors Involved in Brucella Infection of Hela Cells

Published on: August 5, 2016

Collection and Processing of Lymph Nodes from Large Animals for RNA Analysis: Preparing for Lymph Node Transcriptomic Studies of Large Animal Species
12:53

Collection and Processing of Lymph Nodes from Large Animals for RNA Analysis: Preparing for Lymph Node Transcriptomic Studies of Large Animal Species

Published on: May 19, 2018

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Last Updated: Jun 10, 2026

Diagnosis and Surgical Treatment of Human Brucellar Spondylodiscitis
06:23

Diagnosis and Surgical Treatment of Human Brucellar Spondylodiscitis

Published on: May 23, 2021

Microscopy-based Assays for High-throughput Screening of Host Factors Involved in Brucella Infection of Hela Cells
15:29

Microscopy-based Assays for High-throughput Screening of Host Factors Involved in Brucella Infection of Hela Cells

Published on: August 5, 2016

Collection and Processing of Lymph Nodes from Large Animals for RNA Analysis: Preparing for Lymph Node Transcriptomic Studies of Large Animal Species
12:53

Collection and Processing of Lymph Nodes from Large Animals for RNA Analysis: Preparing for Lymph Node Transcriptomic Studies of Large Animal Species

Published on: May 19, 2018

Main Results:

  • Widespread vaccination in animals is identified as the most rapid and effective control measure.
  • Controlling brucellosis in small ruminants presents greater challenges than in cattle, often due to political and socioeconomic factors.
  • A decrease in human brucellosis cases is the primary indicator of successful animal brucellosis control efforts.

Conclusions:

  • Effective brucellosis control necessitates sustained commitment from governmental agencies and international organizations.
  • Developing countries often require external resources and expertise for successful brucellosis management.
  • Continued research into alternative vaccines, diagnostic tests, and treatments is essential for advancing control strategies.