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Updated: Jun 10, 2026

Asthma Detection Research Based on Voice Signal Processing and Machine Learning
Published on: July 22, 2025
Computer-aided intelligent system for diagnosing pediatric asthma
Maryam Zolnoori1, Mohammad Hossein Fazel Zarandi, Mostafa Moin
1Academic Center for Education, Culture and Research, Tarbiat Modares University, Tehran, Iran. M.Zolnoori@gmail.com
Insights
A new fuzzy system aids asthma diagnosis by analyzing patient-reported symptoms. This tool improves diagnostic accuracy, especially in underserved regions, by providing clear asthma possibility scores.
Area of Science:
- Medical Informatics
- Pulmonology
- Artificial Intelligence in Healthcare
Background:
- Asthma is a prevalent chronic inflammatory lung disease with significant underdiagnosis, particularly in developing nations due to limited healthcare access.
- Barriers to accurate asthma diagnosis include a lack of specialist access and inadequate laboratory facilities, leading to delayed or missed treatment.
- Patient perception of disease symptoms is crucial but often underutilized in standard diagnostic pathways.
Purpose of the Study:
- To develop and evaluate a novel patient-based fuzzy system designed to enhance the diagnostic process for asthma.
- To address critical issues in asthma diagnosis, including patient-centric data representation and algorithmic inference based on patient responses.
- To provide a user-friendly interface for data capture and generate actionable outputs for both patients and physicians regarding asthma likelihood.
Main Methods:
- Development of a modular fuzzy system incorporating patient-reported variables and algorithmic inference.
- Implementation of a front-end interface for efficient patient data collection.
- Evaluation of the system's efficacy using a study sample of 139 asthmatic and 139 non-asthmatic children (age 6-18).
Main Results:
- The developed fuzzy system demonstrated high diagnostic performance in the study sample.
- The system achieved a sensitivity of 88% and a specificity of 100% for asthma diagnosis at a cutoff value of 0.7.
- The system provides an output score (0-10) indicating the possibility of asthma for both patients and physicians.
Conclusions:
- The patient-based fuzzy system represents a promising tool for improving asthma diagnosis, particularly in resource-limited settings.
- The system's high sensitivity and specificity suggest its potential to reduce underdiagnosis and facilitate timely intervention.
- This approach leverages patient perception and algorithmic analysis to offer a more accessible and effective method for asthma assessment.
Abstract:
Asthma is a lung chronic inflammatory disorder estimated between 1.4% and 27.1% in different area of the world. Result of various studies show that asthma is usually underdiagnosed especially in developing countries, because of limitations on access to medical specialists and laboratory facilities. In this paper, we report on the development and evaluation of a novel patient-based fuzzy system that promotes the diagnosis method of asthma. The design of this application addresses five critical issues included: 1) modular representation of asthma diagnostic variables regard to patients' perception of the disease, 2) algorithmic approaches conducting inference of diagnosing based on patient's response to questions, 4) front-end mechanism for capturing data from patient, 5) output for both patient and physician regard to asthma possibility. for the system output score (0-10) the efficacy of this system calculated in the study sample included 139 asthmatic patients and 139 non-asthmatic patients (age range 6-18) reinforce the sensitivity of 88% and specificity of 100% for cut off value 0.7.
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