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Human cardiovascular model and applications
K Y Zhu1, Alvin Ang, Rajendra Acharya U
1Department of Electronics & Computer Engineering, Ngee Ann Polytechnic, Clementi, Singapore. zku2@np.edu.sg
Insights
A new human cardiovascular model accurately simulates hemodynamic signals, aiding early diagnosis of cardiovascular diseases (CVDs). This tool can also model hypertension for developing blood pressure regulation systems.
Area of Science:
- Physiology and Biomedical Engineering
- Computational Modeling of Biological Systems
Background:
- Cardiovascular diseases (CVDs) affect the heart and blood vessels, necessitating accurate diagnostic tools.
- Hemodynamic signals, including blood pressure, flow rates, and volumes, are crucial for diagnosing CVDs.
- Early and accurate diagnosis of CVDs is essential for effective patient treatment.
Purpose of the Study:
- To develop a human cardiovascular model capable of simulating various hemodynamic signals.
- To validate the model's accuracy in representing human arterial blood pressure.
- To explore the model's application in simulating hypertensive patients for control system design.
Main Methods:
- Development of a computational human cardiovascular model.
- Simulation of hemodynamic signals such as blood pressure, flow rates, and volumes.
- Signal verification and stability analysis of the developed model.
Main Results:
- The developed model accurately simulates human hemodynamic signals, particularly arterial blood pressure.
- The model demonstrates potential for simulating hypertensive conditions.
- Signal verification confirms the model's reliability.
Conclusions:
- The human cardiovascular model provides an accurate representation of hemodynamic signals.
- This model serves as a valuable tool for diagnosing cardiovascular diseases and simulating hypertension.
- Further applications in designing blood pressure regulation control systems are feasible.
Abstract:
Cardiovascular diseases (CVDs) can be known as a class of diseases which affect different parts of the cardiovascular system such as the heart or blood vessels. Hemodynamic signals are an important tool used by doctors to diagnose the type of CVD occurred in a patient. Diagnosing the correct type of CVD in a patient early will allow the patient to have the suitable medical treatment. Some examples of CVDs include coronary heart disease, cerebrovascular disease and peripheral arterial disease. A human cardiovascular model is developed in order to simulate different hemodynamic signals of the cardiovascular system. The hemodynamic signals include the blood pressures, flow rates and volumes in various part of the cardiovascular system. This paper presents a model which is able to simulate hemodynamic signals and they are able to represent the human arterial blood pressure accurately. Hence this model can also be used to simulate hypertensive patients in order to design control systems for regulation of blood pressure. Signal verification has been performed and the stability of the model is being investigated. Applications of the human cardiovascular model are also presented.
