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Multi-Faceted Mass Spectrometric Investigation of Neuropeptides in Callinectes sapidus
Published on: May 31, 2022
Identification of neuropeptide Y-like conopeptides from the venom of Conus betulinus
Xuechen Wu1, Xiaoxia Shao, Zhan-Yun Guo
1Institute of Protein Research, Tongji University, Shanghai, China.
Acta Biochimica Et Biophysica Sinica
|August 14, 2010
Abstract:
Neuropeptide Y (NPY) is a ubiquitous endocrine neuropeptide found in vertebrate and invertebrate. In our present work, two NPY-like exocrine conopeptides (designated as cono-NPYs) were first identified in the venom of cone snails. Both cono-NPYs showed sequence characteristics of invertebrate NPYs, suggesting that some exocrine venom peptides are probably evolved from the preexisting endocrine peptides during the evolution of cone snails.
