Related Experiment Video
Updated: Jun 10, 2026

Characterization of Metabolic Status in Nonhuman Primates with the Intravenous Glucose Tolerance Test
Published on: November 13, 2016
Glucose-6-phosphate dehydrogenase deficiency and cardiac surgery
1Advanced Cardiac Centre, Department of Anaesthesiology and Critical Care, PGIMER, Chandigarh, India. neeti_dogra@rediffmail.com
Abstract:
Cardiac surgery involving cardiopulmonary bypass (CPB) in its conventional form involves many processes leading to free radical production, such as perioperative ischemia, reperfusion, circulation of whole body blood through the CPB circuit, hypothermia and acidosis. The red blood cells of a glucose-6-phosphate dehydrogenase (G6PD)-deficient person are unable to scavenge these free radicals, resulting in haemolysis. Here, we describe the successful anaesthetic management of two G6PD-deficient children who underwent cardiac surgery, on and off CPB, without any obvious haemolytic reaction, followed by a discussion of the disorder, with specific consideration of perioperative management of such cases.
Related Concept Videos
Glucose Transporters
Facilitated diffusion-glucose transporters (GLUTs) are encoded by the solute-linked carrier (SLC) family 2, subfamily A gene family, or SLC2A. The 14 GLUT protein members are distributed into three classes:
Hypoglycemia and Glucagon
Glycolysis: Preparatory Phase
Cardiomyopathy VII: Pre and Post Operative Nursing Management
Energy-requiring Steps of Glycolysis
Inborn Errors of Metabolism