HydroCoils, occlusion rates, and outcomes: a large single-center study

Area of Science:

• Neurosurgery
• Interventional Radiology
• Biomaterials Science

Background:

• Cerebral aneurysms pose a significant risk of rupture and long-term morbidity.
• HydroCoils are designed for enhanced volumetric packing within aneurysms compared to traditional platinum coils.
• Increased packing is hypothesized to reduce aneurysm recurrence and rupture risk.

Purpose of the Study:

• To evaluate the impact of HydroCoil utilization on aneurysm occlusion and recurrence rates.
• To determine if the proportion of HydroCoil used influences treatment outcomes.
• To assess the safety and efficacy of HydroCoils in cerebral aneurysm treatment.

Main Methods:

• Retrospective analysis of 328 patients treated for cerebral aneurysms over 5 years.
• Categorization of patients into four groups based on the proportion of HydroCoil used (0%-19%, 20%-49%, 50%-69%, 70%-100%).
• Assessment of initial and follow-up angiographic occlusion rates, procedural complications, and recurrence rates.

Main Results:

• Follow-up data available for 270 patients (average 13 months).
• Complete occlusion rates were 31% immediately post-coiling and 64.8% at follow-up.
• A statistically significant trend for greater occlusion was observed when >70% HydroCoil was used (P = .025).
• Overall recurrence rate was 15.5%, with no significant difference between groups based on HydroCoil proportion.

Conclusions:

• HydroCoils demonstrate comparable overall results to other reported series for aneurysm occlusion.
• Using >70% HydroCoil significantly increases occlusion rates compared to <20% usage.
• No significant difference in recurrence or retreatment rates was found across different proportions of HydroCoil use.