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Related Experiment Video

Updated: Jun 10, 2026

Treatment Model for Young Patients with Psychogenic Erectile Dysfunction and Resultant Infertility

Treatment Model for Young Patients with Psychogenic Erectile Dysfunction and Resultant Infertility

Published on: May 30, 2025

Perceived ejaculate volume reduction in patients with erectile dysfunction: psychobiologic correlates.

Giovanni Corona¹, Valentina Boddi, Mauro Gacci

¹Sexual Medicine and Andrology Unit, Department of Clinical Physiopathology, University of Florence, Florence, Italy.

Journal of Andrology

|August 14, 2010

Summary

This summary is machine-generated.

Perceived ejaculate volume reduction (PEVR) is linked to several health conditions and medications in men with erectile dysfunction (ED). Addressing PEVR may improve overall sexual performance and satisfaction for couples.

Related Experiment Videos

Last Updated: Jun 10, 2026

Treatment Model for Young Patients with Psychogenic Erectile Dysfunction and Resultant Infertility

Treatment Model for Young Patients with Psychogenic Erectile Dysfunction and Resultant Infertility

Published on: May 30, 2025

Area of Science:

Urology
Andrology
Sexual Medicine

Background:

Disorders of orgasm/ejaculation, including perceived ejaculate volume reduction (PEVR), are common issues affecting male sexual health.
Erectile dysfunction (ED) often co-occurs with other sexual dysfunctions, necessitating a comprehensive evaluation.

Purpose of the Study:

To investigate the specific clinical and biochemical factors associated with PEVR in a large cohort of men seeking consultation for ED.
To identify predictors of PEVR and its impact on sexual function and relationships.

Main Methods:

A cross-sectional study of 3141 patients with ED, excluding those with a history of prostate surgery.
Evaluation included clinical data, biochemical markers, and the Structured Interview on Erectile Dysfunction to assess organic, relational, and intrapsychic factors.
Multivariate analysis was used to adjust for confounders such as age, BMI, smoking, and medications.

Main Results:

PEVR was significantly associated with androgen deprivation therapy, alpha-blockers, SSRIs, and ACE inhibitors/ARBs.
Higher prevalence of diabetes mellitus and hypogonadism was observed in patients with PEVR.
Severe ED, hypoactive sexual desire (HSD) in patients and partners, and impairments in relational/intrapsychic components of ED were independently associated with PEVR.

Conclusions:

PEVR is independently associated with hypogonadism, diabetes mellitus, severe ED, and HSD in patients and partners.
PEVR plays a significant role not only in reproductive outcomes but also in the overall sexual performance and satisfaction within a couple.