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Updated: Jun 10, 2026
Modified Experimental Conditions for Noise-Induced Hearing Loss in Mice and Assessment of Hearing Function and Outer Hair Cell Damage
Published on: February 10, 2023
Frequency-dependent and longitudinal changes in noise-induced hearing loss in a bottlenose dolphin (Tursiops
James J Finneran1, Carolyn E Schlundt
1US Navy Marine Mammal Program, Space and Naval Warfare Systems Center Pacific Code 7151, 53560 Hull Street, San Diego, California 92152, USA.
Abstract:
Temporary threshold shift (TTS) was measured in a bottlenose dolphin (Tursiops truncatus) after exposure to 16-s tones at 3 and 20 kHz to examine the effects of exposure frequency on the onset and growth of TTS. Thresholds were measured approximately one-half octave above the exposure frequency using a behavioral response paradigm featuring an adaptive staircase procedure. Preliminary data provide evidence of frequency-specific differences in TTS onset and growth, and increased susceptibility to auditory fatigue after exposure to 3-kHz tones compared to data obtained two years earlier.
