Related Experiment Video
Updated: Jun 10, 2026

Mechanism of Kemeng Fang's Inhibition of Podocyte Apoptosis in Rats with Membranous Nephropathy through the PI3K/AKT Signaling Pathway
Published on: August 23, 2024
Management of idiopathic membranous nephropathy
Claudio Ponticelli1, Patrizia Passerini
1Humanitas Hospital, Division of Nephrology, Via Manzoni 56, 20089 Rozzano, Milan, Italy. claudio.ponticelli@fastwebnet.it
Importance Of The Field:
Idiopathic membranous nephropathy (IMN) can have a variable natural course. Treatments able to induce remission can improve the long-term prognosis. However, the optimal therapy for IMN remains controversial.
Area Covered In This Review:
We reviewed the historical and current literature from 1979 to 2010 regarding the natural course of IMN and the possible treatments giving special emphasis to randomized controlled trials and to more recent approaches.
What The Reader Will Gain:
The reader will gain a comprehensive review of the available treatments of IMN. A personal therapeutic algorithm for nephrotic patients with IMN is also provided.
Take Home Message:
At least five different treatments showed efficacy in many (but not all) patients with IMN.
Related Concept Videos
Nephrotic Syndrome II : Assessment and Medical Management
Nephrotic Syndrome III : Nursing Management
Chronic Kidney Disease III: Interprofessional Care
Nephrotic Syndrome I : Introduction
Acute Kidney Injury V: Interprofessional Care
Chronic Kidney Disease IV: Nursing Management
