Jove
Visualize
Contact Us

Related Concept Videos

Toxicity Testing in Animals01:23

Toxicity Testing in Animals

Toxicity tests in animals are grounded on two main assumptions: first, the effects observed in laboratory animals can be extrapolated to humans, especially when adjusted for body surface area; second, high-dose exposure in animals is essential to identify potential human hazards from lower doses. This is based on the quantal dose-response concept, which faces the challenge of extrapolating results from relatively few test animals to much larger human populations. For example, a 0.01% incidence...
Types of Toxins01:36

Types of Toxins

Humans continually engage with an environment rich in potentially harmful chemicals. These are introduced to our bodies through inhalation, ingestion, or skin contact. These chemicals exist in various forms, such as air and environmental pollutants, agricultural chemicals, organic solvents, and heavy metals.
Air pollutants, primarily gases, pose significant threats to respiratory health, leading to conditions like hypoxia, lung cancer, and in extreme cases, death.
Environmental pollutants like...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Development of a First-tier Risk Assessment Tool for Occupational Hazards Among Public Officials.

Safety and health at work·2026
Same author

Hematopoietic carcinogen assessment in bulk chemical products and air samples: focus on benzene exposure among subway maintenance workers.

Inhalation toxicology·2026
Same author

Real-Time Assessment of Black Carbon Peaks Among Workers Exposed to Diesel Engine Exhaust Emissions.

Safety and health at work·2026
Same author

Development of Korean CARcinogen EXposure: 2020 update on IARC group 1 carcinogens.

Annals of work exposures and health·2025
Same author

Development of Korean CARcinogen EXposure: IARC Group 2A Carcinogens.

Safety and health at work·2025
Same author

Development and Application of Standard Codes for the National Exposure Surveillance System Utilizing Korea's Nationwide Exposure Database.

Safety and health at work·2025
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Video

Updated: Jun 10, 2026

Development of a Nose-only Inhalation Toxicity Test Chamber That Provides Four Exposure Concentrations of Nano-sized Particles
05:07

Development of a Nose-only Inhalation Toxicity Test Chamber That Provides Four Exposure Concentrations of Nano-sized Particles

Published on: March 18, 2019

Extensive changes to occupational exposure limits in Korea.

Jee Yeon Jeong1, Sangjun Choi, Young Lim Kho

  • 1Department of Occupational and Environmental Health, Yongin University, Cheoingu, Yongin, South Korea. jyjung@yongin.ac.kr

Regulatory Toxicology and Pharmacology : RTP
|August 17, 2010
PubMed
Summary
This summary is machine-generated.

Korea revised its occupational exposure limits (OELs) for 126 chemicals, significantly lowering limits for 58 substances. This update enhances worker protection against hazardous chemical exposures.

More Related Videos

Assessment of the Acute Inhalation Toxicity of Airborne Particles by Exposing Cultivated Human Lung Cells at the Air-Liquid Interface
10:10

Assessment of the Acute Inhalation Toxicity of Airborne Particles by Exposing Cultivated Human Lung Cells at the Air-Liquid Interface

Published on: February 23, 2020

In vitro Cannabis Exposures of Lung Epithelial Cells at the Air-Liquid Interface
07:05

In vitro Cannabis Exposures of Lung Epithelial Cells at the Air-Liquid Interface

Published on: June 20, 2025

Related Experiment Videos

Last Updated: Jun 10, 2026

Development of a Nose-only Inhalation Toxicity Test Chamber That Provides Four Exposure Concentrations of Nano-sized Particles
05:07

Development of a Nose-only Inhalation Toxicity Test Chamber That Provides Four Exposure Concentrations of Nano-sized Particles

Published on: March 18, 2019

Assessment of the Acute Inhalation Toxicity of Airborne Particles by Exposing Cultivated Human Lung Cells at the Air-Liquid Interface
10:10

Assessment of the Acute Inhalation Toxicity of Airborne Particles by Exposing Cultivated Human Lung Cells at the Air-Liquid Interface

Published on: February 23, 2020

In vitro Cannabis Exposures of Lung Epithelial Cells at the Air-Liquid Interface
07:05

In vitro Cannabis Exposures of Lung Epithelial Cells at the Air-Liquid Interface

Published on: June 20, 2025

Area of Science:

  • Occupational Health and Safety
  • Toxicology
  • Industrial Hygiene

Background:

  • Occupational Exposure Limits (OELs) are crucial for protecting workers from chemical hazards.
  • Korea's Ministry of Labor (MOL) established the first OELs in 1986, initially mirroring US standards.
  • For twenty years, OELs remained largely unchanged, with only three substances updated before 2006.

Purpose of the Study:

  • To revise outdated Occupational Exposure Limits (OELs) in Korea.
  • To enhance worker protection by updating chemical exposure standards.
  • To address the need for scientifically current OELs based on toxicological evidence.

Main Methods:

  • A Hazardous Agents Review Committee identified 126 chemicals requiring OEL revision.
  • Research funding was provided for academic and toxicological studies to gather evidence.
  • The MOL reviewed evidence to establish revised OELs for selected chemicals.

Main Results:

  • Revised OELs for 126 chemicals were notified between 2007 and 2008.
  • Significantly, OELs for 58 substances were lowered to half or less of their original values.
  • This represents the most substantial revision of OELs in Korean history.

Conclusions:

  • The 2007-2008 OEL revisions represent a major advancement in Korean occupational health.
  • Lowered exposure limits for numerous chemicals provide enhanced protection for Korean workers.
  • The process established a precedent for evidence-based OEL updates in Korea.