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Updated: Jun 10, 2026

Mouse Kidney Transplantation: Models of Allograft Rejection
Published on: October 11, 2014
Osseous metaplasia in a kidney allograft
Stanislas Bataille1, Laurent Daniel, Tristan Legris
1Université de la Méditerranée, Assistance Publique des Hôpitaux de Marseille, Centre de Néphrologie et Transplantation rénale, Hôpital Conception, 147 Boulevard Baille, Marseille Cedex 05, France. stanislas.bataille@ap-hm.fr
Abstract:
Osseous metaplasia is defined by the presence of heterotopic normal bone tissue in a soft tissue. The bone matrix is associated with osteoblasts, osteoclasts, adipocytes and haematopoietic stem cells. Osseous metaplasia pathophysiology is not well known, but many factors have been incriminated including chronic inflammation and chronic ischaemia. We describe the second case of osseous metaplasia in a kidney allograft. Numerous factors might favour its development including factors linked to transplantation failure environment.
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