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Mania and Antimanic Drugs: Overview01:24

Mania and Antimanic Drugs: Overview

Mania, a psychological condition characterized by elevated mood, increased energy, and reduced sleep need, is part of the bipolar disorder cycle. The exact cause of mania isn't entirely known, but it is thought to be a combination of genetic, environmental, and neurological factors. Bipolar disorder involves alternating manic and depressive episodes. Mood stabilizers like lithium, antipsychotics, and anticonvulsants help manage these episodes. Lithium carbonate is particularly effective as a...
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Related Experiment Video

Updated: Jun 10, 2026

Developing a Rat Model for Bipolar Disorder
04:42

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Published on: May 2, 2025

Amisulpride induced mania.

Ashish Aggarwal1, Manish Jain, Ashish Khandelwal

  • 1Department of Psychiatry, Indira Gandhi Medical College, Shimla-171001, Himachal Pradesh, India.

Indian Journal of Pharmacology
|August 17, 2010
PubMed
Summary
This summary is machine-generated.

Amisulpride, an antipsychotic, is typically used for schizophrenia. However, this report details a schizophrenia patient who experienced a manic episode while undergoing treatment with amisulpride.

Keywords:
Amisulprideadverse drug reactionmania

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Area of Science:

  • Psychiatry and Pharmacology

Background:

  • Amisulpride is an atypical antipsychotic medication.
  • It is commonly prescribed for schizophrenia and dysthymia.
  • It is also utilized as an adjunctive treatment for bipolar disorders.

Purpose of the Study:

  • To report an unusual adverse effect of amisulpride.
  • To highlight the potential for manic episodes in schizophrenia patients on amisulpride.

Main Methods:

  • Case report of a schizophrenia patient.
  • Observation of clinical presentation during amisulpride treatment.

Main Results:

  • The patient, diagnosed with schizophrenia, developed a manic episode.
  • This occurred despite being treated with amisulpride.

Conclusions:

  • Amisulpride may be associated with the induction of manic episodes, even in patients with schizophrenia.
  • Further investigation into this adverse effect is warranted.