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Assignment of human prochymosin pseudogene to chromosome 1
1Department of Biochemistry and Biotechnology, University of Kuopio, Finland.
Genomics
|June 1, 1991
Abstract:
Chymosin is an extremely specific aspartatic protease responsible for milk coagulation. Chymosin is expressed in a number of mammalian offspring, yet its presence in the gastric tissue of human infants remains a matter of controversy. In any event, the human genome contains chymosin-related sequences that probably represent a pseudogene. Using DNA obtained from human x hamster somatic cell hybrids as the template and polymerase chain reaction, we have mapped the human prochymosin pseudogene to chromosome 1.